BIO Protocol in-depth research report: the decentralized science (DeSci) platform fully supported by Binance

1. Project Introduction

1. Basic project information

BIO Protocol is a decentralized science (DeSci) platform designed to promote the funding, development and sharing of intellectual property (IP) for biotechnology research through a decentralized autonomous organization (DAO) model. Its goal is to address the uneven distribution of funding for traditional biomedical research and encourage research into rare diseases, longevity research, and other emerging health challenges.

BIO Protocol’s origins can be traced back to its team’s work on early biomedical tokenization platform Molecule and longevity science community VitaDAO, while BIO Protocol was officially launched as an independent project in 2024.

2. Project development history

( 1 ) Early exploration stage

At the beginning of 2023, the BIO Protocol team has begun to build the De-Sci ecosystem, using the successful experience accumulated in Molecule and VitaDAO as the cornerstone to start pioneering exploration. They deeply analyzed the pain points of traditional scientific research and combined with cutting-edge blockchain technology to lay a solid foundation for subsequent development.

( 2 ) Project startup and initial development

In late 2024, BIO Protocol was officially established and began to build the BioDAOs network, attracting the participation of scientists, patients and investors, and promoting research projects in multiple scientific fields.

( 3 ) Important milestones

In November 2024, Binance Labs made its first De-Sci investment in BIO Protocol, providing important financial support and industry recognition for the development of the project.

In December 2024, BIO Protocol completed the BIO Genesis token issuance, raising more than $33 million. At the same time, the BIO token airdrop plan was launched to attract in-depth participation from early supporters and active community members around the world, paving the way for the rapid expansion of the project ecology and stimulating community vitality.

In January 2025, BIO tokens will be launched on Binance Launchpool, and are planned to be launched on Ethereum, Solana and Base networks to comprehensively expand token circulation channels, enhance project influence and market coverage, and facilitate subsequent capital flows within the ecosystem. Value exchange builds diverse bridges.

3. Core team background

The core team of BIO Protocol is composed of senior experts in the fields of blockchain and biotechnology. The main personnel include:

Paul Kohlhaas, who wears many hats, is the co-founder of BIO Protocol, founder and CEO of Molecule, and co-founder of VitaDAO. He has profound knowledge in the field of integration of blockchain and biotechnology. Previously worked in ConsenSys and Swiss government blockchain projects.

Clemens Ortlepp, co-founder and chief product officer (CPO) of BIO Protocol and founder of MTX Studio, focuses on decentralized technology innovation. Lead the creation of BIO Protocol client products to ensure that the platform has a friendly interactive interface and efficient operating procedures.

James Sinka focuses on R&D and community sectors. On the one hand, he has deep roots in blockchain technology research and development, ensuring that the underlying technical structure of BIO Protocol is stable, efficient, and continuously iteratively optimized; on the other hand, he is good at community operations, uniting patients and scientists scattered around the world. , enthusiasts and other group forces to create an active and creative community ecology.

Jose Pinto, legal consultant, is familiar with laws and regulations in many places around the world, especially in the field of cryptocurrency. Guarantee the thorny road of project compliance operation and cope with regulatory challenges, and provide professional legal support for every detail, from the establishment of business structure in the early stages of project launch, compliance review of token issuance, to contract formulation and intellectual property protection in daily operations. Ensure that projects move forward steadily in a complex and ever-changing legal environment and avoid hindering development due to legal risks.

Leonard Boltz, a product expert, is responsible for carving out the details of every user contact and dismantling BIO Protocol's grand vision into practical and convenient tools. We are committed to creating the ultimate user experience so that users with different knowledge levels and technical backgrounds can easily get started, seamlessly integrate into the ecosystem, and promote the large-scale popularization of the project.

Nate Hindman, head of growth, always keeps a close eye on market dynamics, user needs and industry trends. Through multiple means such as formulating precise marketing strategies, expanding cooperation channels, and holding online and offline activities, we are committed to expanding the influence of BIO Protocol and attracting more scientists, patients, and members of the cryptocurrency community to join.

2. Business model

1. Operation mode

BIO Protocol is the financial layer of decentralized science (DeSci), aiming to accelerate the flow of capital and talent into on-chain science. The protocol aims to catalyze the on-chain economy of the scientific community (BioDAOs) and create a deep, liquid, and efficient market for scientific IP developed by BioDAOs.

BIO Protocol has 5 core functions:

( 1 ) Curation ( BIO Staking )

BIO token holders join the ecosystem by participating in the selection of new BioDAOs, using a bottom-up approach to fund scientific research. BioDAOs selected by the community will be funded, added to the treasury, and supported by BIO Protocol. Because BIO Protocol relies on high-quality BioDAOs, Curation requires the participation of locked BIOs (vBIOs) to ensure that participants maintain long-term goals consistent with the network.

Through vBIO (Locked BIO), BIO holders can express support for new DAO applications submitted by "operators" (network stakeholders who support the BioDAO incubation phase).

BIO holders use vBIO tokens to select the BioDAOs they wish to adopt. If the DAO they support is approved onto the network, these stakers will receive priority in whitelisted funding rounds, as well as privileged access to DAO products, data, or services.

( 2 ) Funding ​

If the BioDAO application is accepted to join the BIO network, all participants who have pledged vBIO to support the BioDAO can participate in the initial whitelisted seed round of financing.

Through BIO, users can support groundbreaking scientific research from day one and enjoy the same or even better conditions than venture capital institutions (VC) or other institutions.

( 3 ) Liquidity management ( Liquidity )

BioDAOs focus on scientific research, not managing liquidity. BIO Protocol solves this problem by managing the liquidity of the BioDAO secondary market.

BIO Protocol can use BIO tokens and other tokens in its vault to hold assets and provide on-chain liquidity support for the BIO network.

BIO tokens can be paired with BioDAO tokens (such as VITA/BIO, HAIR/BIO) or with other assets (such as BIO/ETH) to build liquidity pools to enable low-cost tokens in the network Convert, accumulate fees and build the protocol’s own liquidity.

( 4 ) Bio/acc Rewards ( Bio/acc Rewards )

BIO Protocol can issue rewards in the form of BIO tokens (i.e. “bio/acc rewards”) to incentivize BioDAOs to achieve key milestones designed to increase network value (e.g. assets under management, AUM).

BIO holders can use bio/acc rewards to incentivize BioDAOs to achieve the following goals:

Ø Provide a certain amount of financial support for on-chain scientific research;

Ø Maintain a certain level of token liquidity;

Ø Develop intellectual property that can enter clinical trials;

Ø Generate sales revenue from consuming products or services.

( 5 ) Meta- Governance

BIO Protocol holds a variety of BioDAO tokens in its vaults and therefore serves as a meta-governance layer, empowering BIO holders to govern a wide range of BioDAOs and scientific IP assets.

2. Ecological construction

The ecological core of BIO Protocol relies on the BioDAO network. Each of these BioDAOs focuses on different subdivided scientific fields. Each BioDAO is an independent and collaborative innovation engine. Its members include patients, scientists, and biotechnology practitioners in related fields. They gather for a common goal and selflessly contribute their own data and funds. , labor force and other resources to form a strong synergy to promote scientific research forward.

Taking the funding link as an example, the project has carefully designed a sophisticated mechanism to accurately guide the flow of funds to specific scientific missions or individual IP assets. When a certain BioDAO locks in to conquer a certain rare disease scientific research project, it quickly launches multiple strategies such as community voting and token incentives, and throws olive branches to all parties around the world who are full of enthusiasm and professional matching for this, attracting financial investment, and at the same time igniting Communicate within the network to accelerate the scientific research process.

3. Successful cases

( 1 ) VitaDAO

Providing more than $5 million in funding for longevity science, with support from Pfizer Ventures and a partnership with Newcastle University.

( 2 ) HairDAO

Focusing on hair loss problems, it owns all DAO patents and consumer products Follicool.

( 3 ) CerebrumDAO

Advancing brain health research, has raised over $1.5 million and entered into a collaboration agreement with Fission Pharma to jointly address mitochondrial dysfunction in neurodegenerative diseases.

( 4 ) ValleyDAO

Focusing on the field of synthetic biology, it has raised more than $2 million and established a collaboration with Imperial College.

( 5 ) AthenaDAO

Promotes women's health research and development, has funded $500,000 in translational research, and currently has 14 intellectual property transactions in progress.

( 6 ) CryoDAO

Advancing the field of cryogenic science, raising over $3 million for the field and establishing project collaborations with Oxford Cryotechnology and Advanced Neural Biosciences.

( 7 ) PsyDAO

Focusing on psychedelic drug research, it launched the OPSY platform, a new platform that uses psychedelic drug trials and data to drive research.

The BIO second group early admission list includes:

( 1 ) Long COVID Labs

Committed to accelerating the development of treatment solutions for more than 100 million long-term COVID-19 patients.

Founder: Rohan Dixit, former Stanford University neuroscientist, medical entrepreneur, and long-term COVID survivor.

( 2 ) Quantum Biology DAO

Developing quantum microscopes to advance biological research.

Founders: Clarice D. Aiello (Ph.D. from MIT, world-leading quantum biology scientist) and Geoff Anders (Executive Director of Leverage Research).

( 3 ) Curetopia

Solve the $1 trillion-plus rare disease problem by uniting families and patient communities.

Founder: Ethan Perlstein, Ph.D. from Harvard University, entrepreneur, Y-Combinator alumnus.

4. Token Economics

$BIO is BIO Protocol’s native governance token. Holders can use $BIO to:

Ø Signal which BioDAO (Curation) is supported;

Ø Vote on future $BIO issuances or distributions;

Ø Implement the network development accelerator program.

$BIO provides holders with the following benefits:

Ø Governance rights of BioDAOs network

Ø Right to participate in early financing rounds of BioDAO

Ø Financial incentives for health data contributions and participation in clinical trials

Ø New health products funded by BioDAO

$BIO is issued by the Bio.xyz Association, a non-profit organization that is the legal steward of BIO's infrastructure and finances.

( 1 ) Initial allocation

Ø Total supply: 3,320,000,000

Ø Circulating supply: 39.05% (15% of which is in the BIO Protocol treasury and requires governance voting to unlock)

Ø Maximum supply: no upper limit, determined by voting by the BIO governance body

New BIO can be minted for future protocol or network growth, but a new contract will need to be deployed to replace the current BIO token contract.

( 2 ) Genesis ’s token distribution

Ø Community: 56% (including: community auction: 20%, community airdrop: 6%, ecosystem incentives: 25%, Molecule ecological fund: 5%)

Ø Early supporters: 13.6%

Ø Early contributors: 21.2%

Ø Consultants: 4.2%

Ø Molecule：5%

( 3 ) $BIO Unlock Plan

Ø Ecosystem incentives (25%): no lock-in

Ø Community airdrop (6%): no lock-in

Ø Community auction (20%): 50% non-locked, 50% linearly unlocked in one year

The tokens received by the remaining parties will be unlocked within 1-6 years respectively.

3. Project Prospects

1. Industry analysis

The DeSci industry in which BIO Protocol operates is an emerging and rapidly developing field that is in the early stages of rapid development. According to a recent chart shared by Messari, half of the top 10 DeSci projects by market capitalization were launched in 2024. The rapid rise of this area of ​​the cryptocurrency market highlights continued innovation and growing interest.

Key drivers of the DeSci industry include the following:

The decentralization trend of scientific research: The allocation of funds for traditional scientific research projects is usually concentrated in the hands of a few institutions. DeSci provides a fairer choice and encourages the global community to participate together.

Decentralized management of intellectual property: Through blockchain technology, scientific research IP can be transparently recorded and distributed. This mechanism helps improve the transparency and efficiency of innovation.

Rapid growth of the biotechnology industry: According to industry research, the global biotechnology market is expected to reach US$850 billion in 2025, with an average annual growth rate of more than 7%. The DeSci platform can capture a piece of this market.

Strong and difficult-to-satisfy market demand: From the perspective of patients, they are suffering from diseases and long for faster access to innovative treatment solutions. They also hope to be deeply involved in scientific research decision-making and have a voice for their own destiny; while some scientists have no ideas. , and looking forward to sufficient financial support and an efficient collaboration platform; investors are looking for emerging investment opportunities in the market, and DeSci is like a gold mine waiting to be excavated, which just meets the urgent demands of all parties.

The traditional scientific research model seems to be stuck in a quagmire, suffering from long-term problems such as uneven distribution of funds, slow transformation of results, and high barriers to scientific research. DeSci uses cutting-edge concepts such as blockchain and tokenization to open up a new scientific research paradigm. At present, DeSci has attracted a large influx of innovators and investors, and many projects have sprung up, covering diverse fields such as longevity, neuroscience, and biotechnology. It is trying to reshape the scientific research ecosystem and inject new ideas into human technological progress. kinetic energy.

2. Development plan

On January 4, 2025, BIO Protocol co-founder Paul Kohhaas released BIO Protocol’s January roadmap, including:

Ø Introducing 10 new DAOs;

Ø Release Rust and EVM startup platform contracts;

Ø Cross-chain $BIO to Solana and Base;

Ø Launching the genesis projects of Curetopia and Long COVID Labs;

Ø Start DeFi liquidity matching;

Ø Release DeScAI agent (in cooperation with Vita Dao);

Ø Conduct the token generation event (TGE) of Quantum Biology DAO;

Ø Start platform audit.

BIO Protocol’s immediate goals:

Ø Further expand the BioDAOs network to attract the participation of more scientists, patients and the cryptocurrency community;

Ø Launch user-friendly tools and platforms to lower the technical threshold for user participation;

Ø Support the active development of the ecosystem through the BIO token incentive mechanism.

BIO Protocol’s long-term goals:

Ø Become a leader in the field of DeSci and establish a global decentralized network for scientific research;

Ø Promote the transformation of scientific research results funded by BioDAOs into the market and achieve a win-win situation of economic and social benefits;

Ø Cooperate with government agencies and traditional scientific research organizations to further promote the decentralized scientific research model.

4. Summary

BIO Protocol is an important innovator in the DeSci industry, providing a fair and transparent collaboration platform for researchers, investors and patient communities by building a decentralized biotechnology research and commercialization ecosystem. Its comprehensive token economic model and strong cooperation network give BIO Protocol significant potential in the rapidly growing DeSci market.

Combining market demand, project team background and industry development trends, $BIO has a high long-term investment value. The initial price fluctuation may be large, but its unique ecological value is expected to gradually emerge in the long term. In addition, as the first DeSci project to issue coins on the Binance platform, it is recommended to give it a certain valuation premium. Investors can allocate an appropriate amount of $BIO based on their risk appetite.

The DeSci industry is still in its infancy, but with the widespread application of blockchain technology and the increasing complexity of biotechnology research, decentralized research funding and commercialization models are expected to become one of the mainstream trends in the future. The success of BIO Protocol may lead more innovative DeSci projects to join this wave.